Spicy Cajun Chicken Alfredo

Featured in: Hearty Comfort Dinners

This dish highlights tender chicken breasts seasoned with bold Cajun spices, pan-seared to golden perfection. Combined with al dente fettuccine, it’s enveloped in a smooth, creamy Alfredo sauce infused with garlic, smoked paprika, and a hint of chili flakes. The sauce’s richness is balanced by freshly grated Parmesan and garnished with fresh parsley for a vibrant finish. An ideal choice for those craving a harmonious blend of heat and creaminess.

Updated on Sat, 15 Nov 2025 13:04:00 GMT
Creamy, spicy Cajun Chicken Alfredo with vibrant parsley garnish, a delicious pasta dinner. Save
Creamy, spicy Cajun Chicken Alfredo with vibrant parsley garnish, a delicious pasta dinner. | smokyfeast.com

A bold, creamy pasta dish featuring tender Cajun-spiced chicken tossed with fettuccine in a rich Alfredo sauce, perfect for spice lovers.

I first discovered Cajun chicken Alfredo while looking for a weeknight meal that balanced comfort with excitement. The spicy kick and silky sauce always satisfy both my family and our guests.

Ingredients

  • Chicken: 2 large boneless skinless chicken breasts, 2 tablespoons Cajun seasoning, 1 tablespoon olive oil
  • Pasta: 340 g (12 oz) fettuccine
  • Alfredo Sauce: 2 tablespoons unsalted butter, 3 cloves garlic (minced), 1 cup (240 ml) heavy cream, 1 cup (100 g) freshly grated Parmesan cheese, 1/2 teaspoon smoked paprika, 1/2 teaspoon chili flakes (optional), salt and black pepper (to taste)
  • Garnishes: 2 tablespoons chopped fresh parsley, extra grated Parmesan cheese

Instructions

Cook Pasta:
Boil fettuccine in salted water until al dente. Reserve 1/2 cup pasta water, drain, and set aside.
Prepare Chicken:
Pat chicken dry and coat evenly with Cajun seasoning.
Cook Chicken:
Heat olive oil in a large skillet over medium-high. Cook chicken 5-6 minutes per side until golden brown and fully cooked. Remove, rest for 5 minutes, then slice thinly.
Start Sauce:
In the same skillet, reduce heat to medium and add butter. Sauté garlic for 1 minute until fragrant.
Finish Sauce:
Add heavy cream, smoked paprika, and chili flakes. Simmer, then whisk in Parmesan until smooth. Season with salt and pepper.
Toss Pasta:
Add cooked fettuccine to sauce, toss to coat. Add pasta water as needed for desired consistency.
Serve:
Top pasta with sliced Cajun chicken. Garnish with parsley and extra Parmesan. Serve immediately.
Sizzling Cajun Chicken Alfredo with tender chicken and fettuccine, a flavorful, homemade meal. Save
Sizzling Cajun Chicken Alfredo with tender chicken and fettuccine, a flavorful, homemade meal. | smokyfeast.com

Every time I bring this Cajun chicken Alfredo to the table, my family gathers around, eager for that first spicy bite. It has become a birthday dinner request and a staple for celebrations.

Allergen Information

This dish includes dairy (cream, butter, cheese) and gluten (pasta). Cajun seasoning may contain mustard or celery. Ensure safe preparation by checking labels for allergen cross-contamination.

Required Tools

You'll need a large pot, skillet, chef's knife, cutting board, tongs, and measuring cups.

Nutritional Information

Per serving: 610 calories, 27 g total fat, 54 g carbohydrates, 38 g protein.

Enjoy tender chicken and alfredo sauce in this appetizing bowl of Cajun Chicken Alfredo pasta. Save
Enjoy tender chicken and alfredo sauce in this appetizing bowl of Cajun Chicken Alfredo pasta. | smokyfeast.com

Serve immediately for the best creamy texture and bold Cajun flavor. Garnish generously with parsley and Parmesan for a crowd-pleasing finish.

Spicy Cajun Chicken Alfredo

Creamy fettuccine with spicy Cajun chicken in a smooth, flavorful Alfredo sauce boosted with garlic and Parmesan.

Prep duration
15 min
Heat time
25 min
Complete duration
40 min
Created by Jackson Reed


Skill Level Medium

Heritage American

Output 4 Portions

Nutrition Labels None specified

What You'll Need

Chicken

01 2 large boneless, skinless chicken breasts
02 2 tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 oz fettuccine

Alfredo Sauce

01 2 tablespoons unsalted butter
02 3 cloves garlic, minced
03 1 cup heavy cream (240 ml)
04 1 cup freshly grated Parmesan cheese (100 g)
05 1/2 teaspoon smoked paprika
06 1/2 teaspoon chili flakes (optional)
07 Salt and black pepper, to taste

Garnishes

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese

Method

Phase 01

Cook pasta: Boil salted water and cook fettuccine until al dente according to package directions. Reserve 1/2 cup pasta water, then drain and set pasta aside.

Phase 02

Season chicken: Pat chicken breasts dry and rub evenly with Cajun seasoning.

Phase 03

Sear chicken: Heat olive oil in a large skillet over medium-high heat. Cook chicken 5-6 minutes per side until cooked through and golden. Remove and rest for 5 minutes before slicing thinly.

Phase 04

Prepare sauce base: Reduce heat to medium in the same skillet, add butter and sauté minced garlic for 1 minute until aromatic.

Phase 05

Finish Alfredo sauce: Stir in heavy cream, smoked paprika, and chili flakes. Simmer gently, then whisk in Parmesan until smooth. Season with salt and pepper.

Phase 06

Combine pasta and sauce: Add cooked fettuccine to the sauce, tossing to coat. Use reserved pasta water sparingly to loosen the sauce if needed.

Phase 07

Serve: Top pasta with sliced Cajun chicken. Garnish with parsley and extra Parmesan. Serve immediatley.

Kitchen Tools

  • Large pot
  • Large skillet
  • Tongs
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons

Allergy Details

Always review ingredients for potential allergens and seek professional medical guidance if unsure.
  • Contains dairy (cream, butter, Parmesan)
  • Contains gluten (fettuccine)
  • May contain mustard or celery from Cajun seasoning

Nutrition Details (per portion)

Values shown are estimates only - please consult healthcare providers for specific advice.
  • Energy: 610
  • Fats: 27 g
  • Carbohydrates: 54 g
  • Proteins: 38 g